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Interaction Analysis

    Name

    MosaicIA - Interaction Analysis

    Software

    ImageJ

    Author

    MOSAIC Group , Center for Systems Biology Dresden (CSBD) , Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) , Dresden, Germany.

    Maintainer

    Krzysztof.Gonciarz

    Source

    MPI-CBG git

    Status

    active

    Category

    Particle analysis, Colocalization

    Interaction Analysis is a tool to analyze the spatial distribution of objects in images. It estimates from an observed particle or object distribution what hypothetical interaction between the objects is most likely to have created this distribution. Detection of the objects (particles) can also be directly done in the plugin. It is part of the MOSAICsuite, which also offers 3D particle tracking, image segmentation, colocalization analysis, and much more. The best way to install it is via the MOSAIC Fiji Update site, as described on the MOSAIC web page. The algorithm is described in Helmuth, Paul, and Sbalzarini (2010[1]). The tool and its use are described in Shivanandan, Radenovic, and Sbalzarini (2013[2]).

    Documentation is available as pdf

    References

    J. A. Helmuth, G. Paul, and I. F. Sbalzarini. Beyond co-localization: inferring spatial interactions between sub-cellular structures from microscopy images. BMC Bioinformatics, 11:372, 2010.

    A. Shivanandan, A. Radenovic, and I. F. Sbalzarini. MosaicIA: an ImageJ/Fiji plugin for spatial pattern and interaction analysis. BMC Bioinformatics, 14:349, 2013.

    [1] J. A. Helmuth, G. Paul, and I. F. Sbalzarini. Beyond co-localization: inferring spatial interactions between sub-cellular structures from microscopy images, BMC Bioinformatics., 11:372, 2010

    [2] A. Shivanandan, A. Radenovic, and I. F. Sbalzarini. MosaicIA: an ImageJ/Fiji plugin for spatial pattern and interaction analysis, BMC Bioinformatics., 14:349, 2013